Foods Linked to ALS

Foods Linked to ALS.jpeg

As explored in my video ALS (Lou Gehrig's Disease): Fishing for Answers, there may be a link in the consumption of the neurotoxin BMAA, produced by algae blooms, and increased risk of ALS. It now appears that BMAA could be found in high concentrations in aquatic animals in many areas of the world.

This could explain ALS clustering around lakes in New Hampshire--up to 25 times the expected rate of ALS with some families eating fish several times a week. Or in Wisconsin, where the most significant ALS risk factor was the past consumption of fish out of Lake Michigan. Or clustering in Finland's Lakeland district, or seafood eaters in France, or around the Baltic sea, building up particularly in fish, mussels and oysters.

When I think of algae blooms I think of the Chesapeake bay near where I live, that gets choked off thanks in part to the poultry industry pollution. And indeed there was a recent report linking BMAA exposure to ALS in Maryland. The ALS victims, all of whom ate Chesapeake Bay blue crabs every week, lived within a half mile of each other, which raised some eyebrows at the Hopkins ALS center. And so researchers tested a few crabs, and two out of three tested positive for BMAA, indicating that the neurotoxin is present in the aquatic food chain of the Chesapeake Bay and is a potential route for human exposure.

To bring the story full circle, things in Guam, where the link between BMAA consumption and ALS was first discovered, are looking up. The ALS epidemic there may have been triggered by their acquisition of guns. Now though, the epidemic appears to be over thanks to near-extinction of the fruit bats they were eating due to over-hunting. But while the rates decline in Guam, neurodegenerative diseases like ALS around the rest of the world are on the rise.

It's plausible that humans have been exposed to some level of BMAA throughout their evolutionary history, but the increase in algae blooms as a result of human activities is probably increasing this exposure. There is a general consensus that harmful algal blooms are increasing worldwide thanks in part to industrialized agriculture (as shown in my video Diet & Amyotrophic Lateral Sclerosis-ALS). More people means more sewage, fertilizer, and manure, which can mean more algae, which may mean more exposure to this neurotoxin, leading to a possible increased incidence of neurodegenerative diseases such as Alzheimer's, Parkinson's, and ALS.

BMAA is considered a strong contender as the cause of, or at least a major contributor to the cause of both endemic and sporadic ALS and Alzheimer's disease, and possibly conferring risk for Parkinson's diseases as well. The ramifications of this discovery are enormous.

As researchers from Australia stated, "With substantial and ever growing evidence that BMAA does play a role in the onset and progression of neurodegenerative diseases, the most important question is, what mode of activity does BMAA exert?" Huh? That's not the most important question we should be asking. The most important question is "How can we reduce our risk?"

We know that the presence of BMAA in aquatic food chains could be a significant human health hazard. There may even be a synergistic toxicity between mercury and BMAA, making certain fish even riskier. Until more is known about the possible link of BMAA to Alzheimer's and ALS, it may be prudent to limit exposure of BMAA in the human diet.

For other neurotoxins found in the food supply, see Amnesic Seafood Poisoning, Essential Tremor and Diet, Ciguatera Poisoning & Chronic Fatigue Syndrome.

Other toxic substances can also build up in the aquatic food chain, for example:

In health,
Michael Greger, M.D.

PS: If you haven't yet, you can subscribe to my free videos here and watch my live, year-in-review presentations:

Image Credit: Peter Miller / Flickr. This image has been modified.

Original Link

Foods Linked to ALS

Foods Linked to ALS.jpeg

As explored in my video ALS (Lou Gehrig's Disease): Fishing for Answers, there may be a link in the consumption of the neurotoxin BMAA, produced by algae blooms, and increased risk of ALS. It now appears that BMAA could be found in high concentrations in aquatic animals in many areas of the world.

This could explain ALS clustering around lakes in New Hampshire--up to 25 times the expected rate of ALS with some families eating fish several times a week. Or in Wisconsin, where the most significant ALS risk factor was the past consumption of fish out of Lake Michigan. Or clustering in Finland's Lakeland district, or seafood eaters in France, or around the Baltic sea, building up particularly in fish, mussels and oysters.

When I think of algae blooms I think of the Chesapeake bay near where I live, that gets choked off thanks in part to the poultry industry pollution. And indeed there was a recent report linking BMAA exposure to ALS in Maryland. The ALS victims, all of whom ate Chesapeake Bay blue crabs every week, lived within a half mile of each other, which raised some eyebrows at the Hopkins ALS center. And so researchers tested a few crabs, and two out of three tested positive for BMAA, indicating that the neurotoxin is present in the aquatic food chain of the Chesapeake Bay and is a potential route for human exposure.

To bring the story full circle, things in Guam, where the link between BMAA consumption and ALS was first discovered, are looking up. The ALS epidemic there may have been triggered by their acquisition of guns. Now though, the epidemic appears to be over thanks to near-extinction of the fruit bats they were eating due to over-hunting. But while the rates decline in Guam, neurodegenerative diseases like ALS around the rest of the world are on the rise.

It's plausible that humans have been exposed to some level of BMAA throughout their evolutionary history, but the increase in algae blooms as a result of human activities is probably increasing this exposure. There is a general consensus that harmful algal blooms are increasing worldwide thanks in part to industrialized agriculture (as shown in my video Diet & Amyotrophic Lateral Sclerosis-ALS). More people means more sewage, fertilizer, and manure, which can mean more algae, which may mean more exposure to this neurotoxin, leading to a possible increased incidence of neurodegenerative diseases such as Alzheimer's, Parkinson's, and ALS.

BMAA is considered a strong contender as the cause of, or at least a major contributor to the cause of both endemic and sporadic ALS and Alzheimer's disease, and possibly conferring risk for Parkinson's diseases as well. The ramifications of this discovery are enormous.

As researchers from Australia stated, "With substantial and ever growing evidence that BMAA does play a role in the onset and progression of neurodegenerative diseases, the most important question is, what mode of activity does BMAA exert?" Huh? That's not the most important question we should be asking. The most important question is "How can we reduce our risk?"

We know that the presence of BMAA in aquatic food chains could be a significant human health hazard. There may even be a synergistic toxicity between mercury and BMAA, making certain fish even riskier. Until more is known about the possible link of BMAA to Alzheimer's and ALS, it may be prudent to limit exposure of BMAA in the human diet.

For other neurotoxins found in the food supply, see Amnesic Seafood Poisoning, Essential Tremor and Diet, Ciguatera Poisoning & Chronic Fatigue Syndrome.

Other toxic substances can also build up in the aquatic food chain, for example:

In health,
Michael Greger, M.D.

PS: If you haven't yet, you can subscribe to my free videos here and watch my live, year-in-review presentations:

Image Credit: Peter Miller / Flickr. This image has been modified.

Original Link

Dr. Greger’s 2015 Live Year-in-Review Presentation

Food as Medicine

View my new live presentation here: Food as Medicine: Preventing and Treating the Most Dreaded Diseases with Diet

Every year I scour the world's scholarly literature on clinical nutrition, pulling together what I find to be the most interesting, practical, and groundbreaking science on how to best feed ourselves and our families. I start with the thousands of papers published annually on nutrition (27,000 this year--a new record!) and, thanks to a crack team of volunteers (and now staff!), I'm able to whittle those down (to a mere 8,000 this year). They are then downloaded, categorized, read, analyzed, and churned into the few hundred short videos. This allows me to post new videos and articles every day, year-round, to NutritionFacts.org. This certainly makes the site unique. There's no other science-based source for free daily updates on the latest discoveries in nutrition. The problem is that the amount of information can be overwhelming.

Currently I have more than a thousand videos covering 1,931 nutrition topics. Where do you even begin? Many have expressed their appreciation for the breadth of material, but asked that I try to distill it into a coherent summary of how best to use diet to prevent and treat chronic disease. I took this feedback to heart and in 2012 developed Uprooting the Leading Causes of Death, which explored the role diet may play in preventing, arresting, and even reversing our top 15 killers. Not only did it rise to become one of the Top 10 Most Popular Videos of 2012, it remains my single most viewed video to date, watched over a million times (NutritionFacts.org is now up to more than 1.5 million hits a month!).

In 2013 I developed the sequel, More Than an Apple a Day, in which I explored the role diet could play in treating some of our most common conditions. I presented it around the country and it ended up #1 on our Top 10 Most Popular Videos of 2013. Then in 2014 I premiered the sequel-sequel, From Table to Able, in which I explored the role diet could play in treating some of our most disabling diseases, landing #1 on our Top 10 Most Popular Videos of 2014.

Every year I wonder how I'm going to top the year before. Knowing how popular these live presentations can be and hearing all the stories from folks about what a powerful impact they can have on people's lives, I put my all into this new 2015 one. I spent more time putting together this presentation than any other in my life. It took me an entire month, and when you see it I think you'll appreciate why.

This year, I'm honored to bring you Food as Medicine, in which I go through our most dreaded diseases--but that's not even the best part! I'm really proud of what I put together for the ending. I spend the last 20 minutes or so (starting at 56:22) going through a thought experiment that I'm hoping everyone will find compelling. I think it may be my best presentation ever. You be the judge.

You can watch it at no cost online, but it is also available on DVD through my website or on Amazon. If you want to share copies with others, I have a five for $40 special (enter coupon code 5FOR40FAM). All proceeds from the sales of all my books, DVDs, downloads, and presentations go to the 501c3 nonprofit charity that keeps NutritionFacts.org free for all, for all time. If you want to support this initiative to educate millions about eradicating dietary diseases, please consider making a donation.

After you've watched the new presentation, make sure you're subscribed to get my video updates daily, weekly, or monthly to stay on top of all the latest.

-Michael Greger

Original Link